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footnotes.

Each public record has its own access date. Original publication dates and evidence limits still matter.

  1. 01
    Manufacturer product page

    CoreAge Rx — GLP-1 Support ↗

    Manufacturer overview and product identity. The newer offer page now supplies an online Supplement Facts panel; see its separate record for current formula and plan information.

    Accessed 2026-09-27
  2. 02
    Manufacturer image

    CoreAge Rx — public front-bottle image ↗

    Front image shows 30 capsules and a 36 mg blend statement. This is not a complete Supplement Facts panel or a CFU/AFU declaration.

    Accessed 2026-09-26
  3. 03
    Manufacturer product page

    Pendulum — GLP-1 Probiotic ↗

    Rendered public offers and consumer-survey qualification checked. Purchase, fulfillment, cancellation and reimbursement were not tested. Survey and preclinical statements are not established clinical outcomes for medication users.

    Accessed 2026-09-26
  4. 04
    Manufacturer label image

    Pendulum — GLP-1 Probiotic facts image ↗

    Visually inspected: 500 million AFU blend, two named strain codes, B. infantis without code, 211 mg chicory inulin, 30 one-capsule servings. Does not establish a per-strain amount or CFU equivalence.

    Accessed 2026-09-26
  5. 05
    Manufacturer research summary

    Pendulum — GLP-1 science page ↗

    Preclinical qualification and 274-person consumer-study description. Not independently controlled evidence of a retail-product weight-loss or prescription-tolerability outcome.

    Accessed 2026-09-26
  6. 06
    Sponsor research directory

    Pendulum — clinical-trials directory ↗

    The two-phase healthy-adult entry still lists estimated 2025 completion and active/fully enrolled wording. Current status and completed findings were not independently established. Other formulas are distinct.

    Accessed 2026-09-26
  7. 07
    Manufacturer product page

    Align — standard 24/7 Digestive Support ↗

    US standard capsule, different count options, incentivized-rating disclosure. Retailer price unverified. Do not transfer to gummies or other Align variants.

    Accessed 2026-09-26
  8. 08
    Manufacturer-linked label image

    Align — 28-serving facts image ↗

    Visually inspected B. longum subsp. longum 35624, 10 mg, one billion CFU at manufacture and ten million cells through best-by. Image describes 28 servings, not all retail counts.

    Accessed 2026-09-26
  9. 09
    Manufacturer guidance

    Align — how to take and store the standard capsule ↗

    Manufacturer count-date and storage statements. Descriptions of effectiveness or timing are commercial claims, not personal advice.

    Accessed 2026-09-26
  10. 10
    Primary trial abstract

    Whorwell et al. — 35624 trial in women with IBS, 2006 ↗

    362 women; four-week intervention and three tested amounts. Only the middle amount significantly separated; highest had formulation problems. Abstract read; not a GLP-1-medication trial or a personal regimen.

    Accessed 2026-09-26
  11. 11
    Primary trial abstract

    Ringel-Kulka et al. — 35624 in a non-patient population, 2017 ↗

    302 randomized, 275 evaluable, four-week intervention. Mean symptom-severity differences were not significant; bloating-free days favored probiotic. Industry affiliation reported. Abstract-only appraisal.

    Accessed 2026-09-26
  12. 12
    Primary research abstract

    Altmann et al. — genome analysis of strain 35624, 2016 ↗

    Genome-based assignment to B. longum subsp. longum explains older infantis naming for 35624. Mechanistic/taxonomic work; not a GLP-1 clinical outcome.

    Accessed 2026-09-26
  13. 13
    Manufacturer product page

    Florastor — standard adult Dual Action ↗

    US adult standard formula and rendered package prices checked. Different Florastor products are separate. Checkout, delivery and returns untested.

    Accessed 2026-09-26
  14. 14
    Manufacturer guidance

    Florastor — product, storage and precaution FAQs ↗

    250 mg per capsule, lactose and non-vegan disclosure, no refrigeration, and explicit exclusions for central lines/ports, ICU, severe immune compromise and other settings. No universal allergy or interaction clearance.

    Accessed 2026-09-26
  15. 15
    Federal evidence fact sheet

    NIH Office of Dietary Supplements — Probiotics ↗

    Strain-specific evidence, label counts, shelf-life and safety context. General review; not endorsement or testing of the retail products.

    Accessed 2026-09-27
  16. 16
    Federal health resource

    NCCIH — Probiotics: Usefulness and Safety ↗

    Evidence limitations and greater potential risk in severe illness or compromised immunity. Access date does not update the underlying studies.

    Accessed 2026-09-27
  17. 17
    Federal consumer resource

    FDA — consumer information about dietary supplements ↗

    Supplement regulation and consumer precautions. Does not establish the safety or effectiveness of a particular product.

    Accessed 2026-09-26
  18. 18
    Federal medicine information

    MedlinePlus — semaglutide injection ↗

    Prescription uses, precautions and adverse-effect information. Does not support treating medication-related symptoms with a probiotic.

    Accessed 2026-09-27
  19. 19
    Federal medicine information

    MedlinePlus — tirzepatide injection ↗

    Prescription information and symptoms needing medical attention. No supplement regimen is derived from this page.

    Accessed 2026-09-26
  20. 20
    Primary laboratory methods study

    Visciglia et al. — probiotic enumeration and shelf-life methods, 2022 ↗

    Flow cytometry and plate-count methods applied to a separate pediatric-targeted synbiotic. Authors report industry roles. Used for measurement context, not a clinical claim or validation of these products.

    Accessed 2026-09-26
  21. 21
    Manufacturer product page

    Visbiome — GI Care capsules ↗

    Standard U.S. 60-capsule bottle with 112.5 billion CFU per capsule. Regular $69.95 price and a separate $62.95 recommendation-discount display; eligibility and checkout unverified. Medical-food, milk and cold-shipping statements are manufacturer records.

    Accessed 2026-09-27
  22. 22
    Visually inspected manufacturer PDF

    Visbiome — June 2026 linked package insert ↗

    12-page insert; pages 1,2,5,9,10 inspected for category, warnings, strain list, AAD summary and storage. Contains milk. Lactose threshold wording differs from product-page trace statement; supplied batch not verified. Historical formulation and current products distinguished; no personal regimen.

    Accessed 2026-09-27
  23. 23
    Manufacturer public product data

    Visbiome — public product variant record ↗

    Default variant regular price $69.95. Does not establish recommendation-discount eligibility, delivered stock, subscription commitment or checkout total.

    Accessed 2026-09-27
  24. 24
    Primary randomized-trial abstract

    Selinger et al. — historical probiotic formulation and antibiotic-associated diarrhea, 2013 ↗

    229 hospitalized adults; historical VSL#3 formulation in sachets. Per-protocol AAD result significant; intention-to-treat result 4.3% versus 8.9%, P=0.19, not significant. No CDAD cases. Abstract-only appraisal; no GLP-1 outcome or direct current-capsule regimen claim.

    Accessed 2026-09-27
  25. 25
    Professional guideline

    AGA — probiotic guideline, June 2020 ↗

    Specified-preparation prevention suggestion differs from ACG 2021. Symptomatic IBS use limited to clinical trials; not a universal retail endorsement. Read with newer population-specific guidance.

    Accessed 2026-09-27
  26. 26
    Professional guideline

    ACG — C. difficile guideline, 2021 ↗

    Recommends against probiotic primary prevention during antibiotics and recurrence prevention. Distinct from antibiotic-associated diarrhea as a broader outcome.

    Accessed 2026-09-27
  27. 27
    Clinical practice update

    AGA — C. difficile infection in IBD, May 2026 ↗

    Published May 15, 2026. Advises against probiotics for primary or secondary CDI prevention in IBD. Population-specific guidance; no prescription treatment instructions reproduced.

    Accessed 2026-09-27
  28. 28
    Professional patient education

    AGA patient center — probiotics ↗

    Strain- and combination-specific context; general education is not proof for every mixture or GLP-1 user.

    Accessed 2026-09-27
  29. 29
    Federal health guidance

    CDC — C. difficile overview ↗

    Contact a healthcare professional for diarrhea during or after antibiotics. Not every case is CDI; symptom assessment and testing are clinical decisions.

    Accessed 2026-09-27
  30. 30
    Federal regulatory explanation

    FDA — Is it really FDA approved? ↗

    Medical foods are not preapproved like drugs; physician-supervision context. Does not adjudicate any reviewed brand's classification or certify safety.

    Accessed 2026-09-27
  31. 31
    Manufacturer offer page

    CoreAge Rx — GLP-1 Support current offer and online panel ↗

    Online panel, delayed-release description, handling and bundle terms. Six-bottle $149 total conflicts with displayed $23.83 unit figure; no checkout, shipment, lot test or clinical outcome independently verified.

    Accessed 2026-09-27
  32. 32
    Scientific consensus

    ISAPP consensus — fermented foods (2021) ↗

    Full text reviewed. Definitions, processing and probiotic distinctions; not a product trial. Industry relationships and organizational funding are disclosed.

    Accessed 2026-09-27
  33. 33
    Primary laboratory-study abstract

    Venema et al. — capsule-within-capsule survival model (2020) ↗

    Abstract and affiliations retrieved through Europe PMC after PubMed challenge. TIM-1 in vitro model, five-strain and oil preparation; no CoreAge test or GLP-1 patient outcome. Full methods and conflict statement not reviewed.

    Accessed 2026-09-27
  34. 34
    Scientific association explanation

    ISAPP — How do probiotics stay alive until they are consumed? ↗

    Viability, dormancy and shelf-life context; no independent validation of a retail lot.

    Accessed 2026-09-27
  35. 35
    Provider shipping reference and supplied service information

    CoreAge Rx: shipping and service information ↗

    Homepage shipping reference; customer service and payment details supplied for this review, without a checkout or timed support test

    Accessed 2026-10-14
  36. 36
    Federal tax guidance; question 14 addresses nutritional supplements

    IRS: nutritional supplements and HSA/FSA medical expenses ↗

    Federal tax guidance; question 14 addresses nutritional supplements

    Accessed 2026-10-14
  37. 37
    Provider service page

    Hello Alpha — weight-care program ↗

    Rendered program page checked; company description of medicine offerings, messaging and nutrition guidance. No enrollment or care tested.

    Accessed 2026-10-15
  38. 38
    Provider membership offer

    Hello Alpha — membership options and FAQ ↗

    Plus+ and lower-tier benefits must be checked separately; medical and membership fees are separate from pharmacy insurance coverage.

    Accessed 2026-10-15
  39. 39
    Provider agreement

    Hello Alpha — terms of use ↗

    30-day renewal, advance cancellation and separate medication-refill handling; confirm the actual accepted plan terms.

    Accessed 2026-10-15